WebMotor neuron diseases or motor neurone diseases (MNDs) are a group of rare neurodegenerative disorders that selectively affect motor neurons, the cells which control voluntary muscles of the body. They include amyotrophic lateral sclerosis (ALS), progressive bulbar palsy (PBP), pseudobulbar palsy, progressive muscular atrophy (PMA), primary … WebCENTRAL PONTINE MYELINOLYSIS osms.it/central-pontine-myelinolysis PATHOLOGY & CAUSES Destruction of myelin sheath around nerve cells in pons due to rapid osmotic …
Isolated Brain Stem Lesion in Children: Is It Acute Disseminated ...
WebDiffuse brainstem lesions are poorly defined, often large abnormalities and include tumors (gliomas and lymphomas) vasculitis (Behçet's disease), traumatic brainstem injury, … Web18 Jan 2024 · Clinical presentation. Clinically osmotic demyelination syndrome presents in a biphasic pattern. The first phase is usually attributable not to the demyelination but rather to the inciting electrolyte … george dumont hospital number
Osmotic demyelination syndrome Radiology Reference …
Central pontine myelinolysis is a neurological condition involving severe damage to the myelin sheath of nerve cells in the pons (an area of the brainstem). It is predominately iatrogenic (treatment-induced), and is characterized by acute paralysis, dysphagia (difficulty swallowing), dysarthria (difficulty speaking), … See more Symptoms depend on the regions of the brain involved. Prior to its onset, patients may present with the neurological signs and symptoms of hyponatraemic encephalopathy such as nausea and vomiting, … See more The currently accepted theory states that the brain cells adjust their osmolarities by changing levels of certain osmolytes like inositol, betaine, and glutamine in response to varying serum osmolality. In the context of chronic low plasma sodium (hyponatremia), the … See more To minimise the risk of this condition developing from its most common cause, overly rapid reversal of hyponatremia, the hyponatremia should be corrected at a rate not exceeding 10 mmol/L/24 h or 0.5 mEq/L/h; or 18 mEq/L/48hrs; thus avoiding demyelination. No … See more The most common cause is overly-rapid correction of low blood sodium levels (hyponatremia). Apart from rapid correction of hyponatraemia, … See more It can be diagnosed clinically in the appropriate context, but may be difficult to confirm radiologically using conventional imaging … See more Though traditionally the prognosis is considered poor, a good functional recovery is possible. All patients at risk of developing … See more • MedPix Images of Osmotic Myelinolysis See more WebAlthough the anatomic detail of brain stem lesions was not described by previous case reports, the present study demonstrates topographic distributions of lesions in the midbrain, pons, and medulla on MR imaging. Midbrain lesions involved the tectum, tegmentum, and red nucleus; and structural involvements varied. Web5 Jun 2015 · Central pontine myelinolysis (CPM) is a neurological disorder caused by damage to the myelin sheath of nerve cells in the brainstem. It is a clinically heterogeneous disease, originally thought to occur only in the central pons area [ 1, 2 ], and later shown to affect areas outside the pons [ 3 ]. george duncan ophthalmologist