Cisplatin and breast cancer

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August undefined, 2024

WebJun 24, 2010 · Concurrent other malignancy at other sites or previous other cancer within the last 5 years, with the exception of adequately treated in situ carcinoma of cervix uteri or basal or squamous cell carcinoma of the skin or a contralateral breast cancer. Serious uncontrolled intercurrent infections. Poor compliance. WebApr 1, 1993 · Pharmacological studies on breast cancer can be cited to Cisplatin [12] .Cisplatin is one of the factors used in chemotherapy; and yet, it is not always used to treat breast...

CISPLATIN + AZD-1775 In Breast Cancer - Full Text View - ClinicalTr…

WebCisplatin is a chemotherapy drug used to treat testicular, ovarian, bladder, head and neck, lung and cervical cancer. It may also be used to treat other cancers. It is best to read this information with our general information about chemotherapy and the … WebIn patients with breast cancer, cellular expression of COL1A1 was associated with ER/PR expression and metastasis status. The increased COL1A1 level was associated with poor survival, especially in patients with ER+ breast cancer. Patients with a high-level of COL1A1 showed better cisplatin-based chemotherapy response. configentity configentity

Cisplatin (chemotherapy drug) - Macmillan Cancer Support

WebApr 12, 2024 · The long-term prognosis for women with recurrent endometrial cancer is also poor. The combination of the chemotherapy drugs cisplatin and paclitaxel has long been … WebBreast Cancer using CISplatin and Gemcitabine . Protocol Code . BRAVGEMP. Tumour Group : Breast: Contact Physician : Dr. Susan Ellard: ELIGIBILITY: Progressive breast cancer after adjuvant anthracyclinebased chemotherapy. - Second or third line treatment of metastatic breast cancer after previous chemotherapy with WebNov 13, 2013 · Cisplatin and paclitaxel are active in triple-negative breast cancer (TNBC). Despite different mechanisms of action, effective predictive biomarkers to preferentially inform drug selection have not been identified. edgar allan poe story about the ticking clock

BCAT1 decreases the sensitivity of cancer cells to cisplatin by ...

Cisplatin - NCI - National Cancer Institute

WebMar 17, 2015 · Compared with carboplatin, cisplatin has shown superior efficacy in the neoadjuvant setting of locally advanced triple-negative breast cancer, with a higher proportion of patients achieving a pathological complete response and a significant improvement in overall survival. WebHere we aim to study the effect of cisplatin at different doses on breast cancer growth and metastasis. Methods: We used cisplatin to treat breast cancer cells, then detected the … config dns server 2008WebApr 14, 2024 · Despite an increase in the incidence of breast cancer worldwide, overall prognosis has been consistently improving owing to the development of multiple targeted … edgar allan poe story the black cat

"WebJul 22, 2024 · Cisplatin represents a promising chemotherapeutic compound in neoadjuvant approaches and in the metastatic setting, but its use is limited by scarce bioavailability, severe systemic side effects and drug resistance. Novel site-directed aptamer-based nanotherapeutics have the potential to overcome obstacles of chemotherapy. " - Cisplatin and breast cancer

Cisplatin and breast cancer

Chemotherapy for Ovarian Cancer Intraperitoneal Chemotherapy

WebJul 12, 2024 · A randomized phase 3 trial of Gemcitabine or Nab-paclitaxel combined with cisPlatin as first-line treatment in patients with metastatic triple-negative breast cancer Biyun Wang, Tao Sun,... WebAug 31, 2015 · Cisplatin is most often used to treat triple-negative breast cancer. In clinical trials , researchers are studying the effectiveness of cisplatin, and its cousin …

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WebFeb 1, 2024 · drowsiness. feeling of fullness in the ears. fever or chills. increased thirst. loss of appetite. loss of balance. loss of hearing. lower back or side pain. nausea or vomiting. WebJun 15, 2024 · Introduction. As one of the main causes of female deaths, breast cancer (BC) is a heterogeneous tumor with different subtypes [1,2].Triple negative breast cancer (TNBC) is the most invasive subtype with a relatively poor prognosis, because it lacks targeted therapies and has a low response to chemotherapy [3,4].Moreover, the disease …

WebApr 13, 2024 · Increasing WNT7A synthesis by invasive cancer cells in breast cancer may improve TGF ... Polanska HH, Vaculovic T, et al. Sensitivity to cisplatin in head and … WebJun 15, 2024 · Introduction. As one of the main causes of female deaths, breast cancer (BC) is a heterogeneous tumor with different subtypes [1,2].Triple negative breast …

WebNov 4, 2024 · Cisplatin is a DNA-intercalating agent that cross-links DNA resulting in interference with RNA transcription and DNA replication activities. If the DNA lesions are … Web2.3 Advanced Ovarian Cancer . Cisplatin for injection has been administered at 75 mg/m. 2 . to 100 mg/m. intravenously per cycle once every 3 to 4 weeks on Day 1. Other doses and combination regimens have been used. 2.4 Advanced Bladder Cancer . Cisplatin for injection has been administered at 50 mg/m. 2 . to 70 mg/m. intravenously per cycle

WebMar 17, 2024 · OMO-1 decreases non-c-MET addicted tumor progression and has additional therapeutic effects in combination with cisplatin. Following intraductal inoculation of luciferase-expressing 4T1 tumor ...

WebUsually, the combination includes a type of chemo drug called a platinum compound (usually cisplatin or carboplatin), and another type of chemo drug called a taxane, such as paclitaxel (Taxol ®) or docetaxel (Taxotere ® ). These drugs are usually given as an IV (put into a vein) every 3 to 4 weeks. edgar allan poe style of writingWeb17 hours ago · The number of drug shortages is forecast to reach a record level this year, imperiling patients. Cancer drugs in short supply include injectable cisplatin, … config do thunderbirdWebOct 22, 2024 · Background Chemotherapy is a standard therapeutic regimen to treat triple-negative breast cancer (TNBC); however, chemotherapy alone does not result in … config do nowayWebMany drugs used to treat breast cancer, including taxanes (docetaxel, paclitaxel, and protein-bound paclitaxel), platinum agents (carboplatin, cisplatin), vinorelbine, eribulin, … config error for mechanic lineWeb2 days ago · Testicular cancer, also known as testicular germ cell tumors (TGCT), is the most common type of cancer in young men. When treated with cisplatin, the tumor cells stop growing and die. This is ... edgar allan poe tamerlane and other poemsWebJan 6, 2024 · Cisplatin is FDA approved for other cancers and has been shown to be an active treatment for breast cancer. AZD1775 is a drug that is designed to block a protein called Wee-1 which may control the ability of certain cancer cells to grow or divide. Cisplatin works by damaging the DNA inside the cancer cells which prevents them from … edgar allan poe tell tale heart poemWebMar 25, 2024 · Here, we report that RRS1 is associated with cisplatin resistance in breast cancer cells. RRS1 silencing increased the sensitivity of MCF-7/DDP cells to cisplatin and inhibited cancer cell proliferation by blocking cell cycle distribution and enhancing apoptosis. AEG-1 (astrocyte elevated gene-1) promotes drug resistance by interfering with the ... config eval f.read