High steacs trial

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August undefined, 2024

WebNov 15, 2024 · The High-STEACS pathway identified 63.4% (1218/1920) of patients as low risk, with five missed events (four index type 1 myocardial infarction and one type 1 myocardial infarction at 30 days) for an NPV of 99.5% (95% CI 99.1% to 99.8%) and sensitivity of 98.0% (95% CI 96.4% to 99.5%). WebNov 7, 2024 · Biological Science Troponin Diagnosing myocardial infarction in the era of high-sensitivity troponin: the High-STEACS trial Cardiovascular Research License CC BY 4.0 Authors: Atul Anand...

Using Administrative Data in a Clinical Trial - eCRUSADers

WebA high-sensitivity troponin assay (hs-TnI) (ARCHITECT stat; Abbott Laboratories, USA) was used to guide clinical decisions This particular assay has a 99th centile upper reference limit of 34 ng/L in men and 16 … WebSep 15, 2024 · Methods: In this stepped-wedge, cluster-randomised controlled trial across ten secondary or tertiary care hospitals in Scotland, we evaluated the implementation of … grand river ortho

Cardiac Troponin Thresholds and Kinetics to …

WebIn the High-STEACS trial,99during the validation phase of the trial (6–12 months), results of the hs-cTnI assay were concealed from the attending clinician and a contemporary cTn assay was used to guide care. WebAug 28, 2024 · The High-STEACS trial 5 is the first randomised trial to evaluate whether the introduction of a high-sensitivity cardiac troponin I assay with a 99th centile diagnostic threshold would reduce subsequent myocardial infarction or cardiovascular death at one year in patients with suspected acute coronary syndrome. WebApr 1, 2024 · This large multicenter trial of close to 31,500 patients from seven centers in Scotland confirms dramatic benefits of adopting an early rule-out strategy, with a 3.3-hour reduction in length of stay in the ED and a 59% decrease in hospital admission, without impacting safety. chinese person in chinese

High-sensitivity troponin in the evaluation of patients

WebSep 20, 2024 · The High-STEACS trial adopted a stepped-wedge, cluster-randomization of 10 hospitals in Scotland, and consisted of 2 phases: a validation phase of 6 months … grand river ontario wikipediaWebThe High-Sensitivity Troponin in the Evaluation of Patients With Acute Coronary Syndrome (High-STEACS) trial, 61 which contributed multiple diagnostic accuracy data sets, was a stepped-wedge cluster RCT that evaluated implementation of an early rule-out pathway in hospitals in Scotland. grand river optometry fergus

"WebAug 28, 2024 · The High-STEACS trial 4 is the first randomised trial to evaluate whether the introduction of a high-sensitivity cardiac troponin I ... High-STEACS on Tuesday 28 August from 15:55 to 16:20 CEST on ... " - High steacs trial

High steacs trial

High-Sensitivity Cardiac Troponin Concentrations at Presentation …

WebJan 14, 2016 · The High-STEACS trial investigators conducted a prospective cohort study of 6,304 consecutively enrolled patients with suspected acute coronary syndrome presenting to four secondary and tertiary care hospitals in Scotland. They measured plasma troponin concentrations at presentation using a high-sensitivity cardiac troponin I assay. WebAug 4, 2016 · The ongoing High-Sensitivity Troponin in the Evaluation of Patients with Acute Coronary Syndrome (High-STEACS) trial 31 is investigating the clinical implications of a high-sensitivity...

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WebDec 19, 2015 · This trial is registered with ClinicalTrials.gov (number NCT01852123). Findings: In patients without myocardial infarction at presentation, troponin concentrations were less than 5 ng/L in 2311 (61%) of 3799 patients, with a negative predictive value of 99·6% (95% CI 99·3-99·8) for the primary outcome. WebAug 29, 2024 · When the STEACS Are High The study enrolled more than 48,000 consecutive patients presenting with chest pain to one of 10 Scottish hospitals, with all patients …

WebNov 1, 2024 · High-Sensitivity Cardiac Troponin Concentrations at Presentation in Patients With ST-Segment Elevation Myocardial Infarction Acute Coronary Syndromes JAMA … WebAug 28, 2024 · The High-STEACS trial makes use of several routine electronic health care data sources that are linked, de-identified, and held in our national safe haven, which is …

WebAug 25, 2024 · The High-STEACS (High-Sensitivity Troponin in the Evaluation of Patients With Acute Coronary Syndrome) pathway missed <1 in every 400 patients tested and did … WebAug 18, 2014 · A high-stakes test is any test used to make important decisions about students, educators, schools, or districts, most commonly for the purpose of …

WebMay 13, 2013 · In ten secondary and tertiary care hospitals across Scotland, the investigators will undertake a stepped wedge cluster randomized controlled trial of the …

WebDec 10, 2024 · study of the High-STEACS trial (High-Sensitivity Troponin in the Evaluation of Patients With Acute Coronary Syndrome). All patients in whom the attending clinician requested car-diac troponin for suspected acute coronary syndrome were eligible for inclusion. We did not enroll patients with ST-segment–elevation myocardial infarction, … chinese person speaking englishWebThe High-STEACS trial makes use of several routine electronic health-care data sources that are linked, de-identified, and held in DataLoch Safe Haven, which is accessible by approved individuals who have undertaken the necessary governance training. Summary aggregate level data and analysis code for this study can be made available upon ... chinese person singingWeb"High-stakes testing" refers to tests that determine whether individual students have reached a specific level of proficiency and that are intended to be used to determine whether the … grand river orthodontics simcoeWebJul 11, 2024 · Trial Protocol and Statistical Analysis Plan Supplement 2. eMethods. eTable 1. Characteristics of the Study Population According to Adjudicated Diagnosis (Type 1 … chinese person with frecklesWebAug 1, 2024 · The High-STEACS trial (High-Sensitivity Troponin in the Evaluation of Patients With Suspected Acute Coronary Syndrome) 7 assessed whether implementing high-sensitivity cardiac troponin testing and the recommendations of the Universal Definition of Myocardial Infarction led to changes in investigation, treatment, and outcomes in patients … chinese perspective on dreams alarm clocksWebOct 14, 2024 · The High-STEACS trial presented an opportunity to explore whether improved diagnostic testing—by transitioning from a conventional to a high-sensitivity cardiac troponin I test, using sex-specific thresholds, and applying the recommendations of the universal definition of MI—had differential impacts on the evaluation, treatment, and outcomes of … chinese perspective on americaWebSep 4, 2024 · MUNICH — The first randomized controlled trial of the latest high-sensitivity cardiac troponin I assay in patients with suspected acute coronary syndrome showed the test increased detection of... chinese perspective on uighurs