WebSep 16, 2015 · Upon stimuli-triggered single cleavage of capping moieties at the focal point and chain terminal, self-immolative dendrimers (SIDs) and linear self-immolative polymers (l-SIPs) undergo spontaneous domino-like radial fragmentation and cascade head-to-tail depolymerization, respectively. WebThe self-immolative polymer segment includes a head end, a tail end, and a plurality of repeating units. The trigger moiety includes a cycloaddition adduct that is covalently coupled to the head end of the self-immolative polymer segment. When the polymer is exposed to an activation temperature, the cycloaddition adduct undergoes retro ...

Self-immolative polymers in biomedicine - PubMed

Web“Stimuli-Responsive Polymer Film that Autonomously Translates a Molecular Detection Event into a Macroscopic Change in Its Optical Properties via a Continuous, Thiol-Mediated Self-Propagating Reaction”, Mohapatra, H.; Kim, H.; Phillips, S. T.*, J. Am. Chem. Soc. 2015, 137, 12498–12501. WebJun 15, 2015 · Self-immolative linear polymers are a recently developed class of materials that typically undergo head-to-tail depolymerization in response to the cleavage of stimuli-responsive end-caps from their termini. These polymers have been inspired by self-immolative dendrimers and oligomers that undergo cascades of cyclization and/or … brazil vs s korea

Hyperbranched Self-Immolative Polymers (hSIPs) for …

WebAug 4, 2010 · This method creates core-shell microcapsules with polymeric shell walls composed of self-immolative polymer networks. The polymers in these networks undergo a head-to-tail depolymerization upon removal of the triggering end group, leading to breakdown of the shell wall and subsequent release of the capsule's liquid interior. We … WebTo demonstrate the concept, we synthesized a self-immolative polymer that amplifies a single cleavage reaction into multiple-release of fluorogenic molecules and confirmed the head to tail disassembly concept. These polymers can be used to prepare highly sensitive molecular sensors with large signal-to-noise ratios. The sensors should be useful ... tab test hvac